Kidney disease often begins quietly, but your body whispers warnings long before total failure. Changes in urination, such as foamy, dark, or blood-tinged urine, may signal that your kidneys are leaking protein or struggling to filter waste. Swelling in your feet, hands, or face can mean fluid is building up because the kidneys can’t keep up. Persistent fatigue, weakness, or dizziness may point to anemia from reduced hormone production in damaged kidneys, while unexplained weight loss, nausea, or vomiting often reflect toxins accumulating silently in your blood.